HPLC Column, Diamond Hydride 2.o, 2.2um, 2.1mm ID x 150mm Length, 120A. Cogent TYPE-C Brand. 1 EA.

Additional Info:

The 70200‑15P‑2 Diamond Hydride 2.0 HPLC Column is engineered for maximum resolving power in HILIC and LC‑MS applications, combining a narrow internal diameter with extended column length. This configuration is ideal for laboratories requiring enhanced separation of complex, closely eluting polar analytes.

High‑Resolution Advantage: 2.1 mm ID × 150 mm

This column length and diameter combination is intentionally selected to deliver:

  • Increased theoretical plates for improved peak separation

  • Greater resolution for structurally similar or closely eluting compounds

  • Lower optimal flow rates, making it highly compatible with LC‑MS systems

Compared to shorter columns or wider‑bore formats, the 150 mm length allows more complete analyte interaction with the stationary phase, enabling finer discrimination in complex biological, pharmaceutical, and metabolomics samples.

Diamond Hydride™ 2.0 Stationary Phase

Built on Cogent TYPE‑C™ silica hydride technology, the Diamond Hydride 2.0 stationary phase provides:

  • Fast equilibration compared to conventional HILIC phases

  • Stable retention mechanisms for reproducible polar compound analysis

  • Improved control of mixed‑mode behavior often encountered in HILIC separations

This stationary phase is especially effective for:

  • Polar and moderately polar peptides

  • Amino acids

  • Metabolites

  • Small biomolecules and challenging polar analytes

The 70200‑15P‑2 Diamond Hydride 2.0 HPLC Column is engineered for maximum resolving power in HILIC and LC‑MS applications, combining a narrow internal diameter with extended column length. This configuration is ideal for laboratories requiring enhanced separation of complex, closely eluting polar analytes.

High‑Resolution Advantage: 2.1 mm ID × 150 mm

This column length and diameter combination is intentionally selected to deliver:

  • Increased theoretical plates for improved peak separation

  • Greater resolution for structurally similar or closely eluting compounds

  • Lower optimal flow rates, making it highly compatible with LC‑MS systems

Compared to shorter columns or wider‑bore formats, the 150 mm length allows more complete analyte interaction with the stationary phase, enabling finer discrimination in complex biological, pharmaceutical, and metabolomics samples.

Diamond Hydride™ 2.0 Stationary Phase

Built on Cogent TYPE‑C™ silica hydride technology, the Diamond Hydride 2.0 stationary phase provides:

  • Fast equilibration compared to conventional HILIC phases

  • Stable retention mechanisms for reproducible polar compound analysis

  • Improved control of mixed‑mode behavior often encountered in HILIC separations

This stationary phase is especially effective for:

  • Polar and moderately polar peptides

  • Amino acids

  • Metabolites

  • Small biomolecules and challenging polar analytes

LC‑MS Ready Performance

The 2.1 mm internal diameter enables reduced flow rates that align naturally with electrospray ionization, helping improve MS sensitivity while reducing solvent load into the mass spectrometer. The additional column length further enhances signal clarity by improving chromatographic resolution upstream of detection.

This makes the 70200‑15P‑2 an excellent choice for:

  • LC‑MS and LC‑MS/MS methods

  • Targeted and untargeted metabolomics

  • High‑resolution biomolecule analysis

System Requirements

  • Typical operating flow rates: ~0.2–0.3 mL/min

  • Requires an HPLC system capable of accurate, stable low‑flow delivery

  • Not all standard HPLC pumps are suitable for reliable operation at these flow rates

Flow‑rate optimization may be further refined based on mobile‑phase viscosity, column temperature, and system pressure limits.

 

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